7AMC
SmBRD3(2), Bromodomain 2 of the Bromodomain 3 protein from Schistosoma mansoni in complex with iBET726
Summary for 7AMC
Entry DOI | 10.2210/pdb7amc/pdb |
Descriptor | Putative bromodomain-containing protein 3, brd3, 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl]benzoic acid, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | bromo domain, methyllysine binding, epigenetic reader domain, inhibitor, complex, protein binding |
Biological source | Schistosoma mansoni (Blood fluke) |
Total number of polymer chains | 2 |
Total formula weight | 31238.01 |
Authors | Schiedel, M.,McDonough, M.A.,Conway, S.J. (deposition date: 2020-10-08, release date: 2021-10-20, Last modification date: 2024-01-31) |
Primary citation | Schiedel, M.,McArdle, D.J.B.,McDonough, M.A.,Conway, S.J. SBM3, Bromodomain 3 from Schistosoma mansoni in complex with iBET726 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.22 Å) |
Structure validation
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