7AMC

SmBRD3(2), Bromodomain 2 of the Bromodomain 3 protein from Schistosoma mansoni in complex with iBET726

Summary for 7AMC

• Entry DOI: 10.2210/pdb7amc/pdb
• Descriptor: Putative bromodomain-containing protein 3, brd3, 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl]benzoic acid, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: bromo domain, methyllysine binding, epigenetic reader domain, inhibitor, complex, protein binding
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 2
• Total formula weight: 31238.01

Authors

Schiedel, M.,McDonough, M.A.,Conway, S.J. (deposition date: 2020-10-08, release date: 2021-10-20, Last modification date: 2024-01-31)

• Primary citation: Schiedel, M.,McArdle, D.J.B.,McDonough, M.A.,Conway, S.J.; SBM3, Bromodomain 3 from Schistosoma mansoni in complex with iBET726; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.22 Å)