7AF1
The structure of Artemis/SNM1C/DCLRE1C with 2 Zinc ions
Summary for 7AF1
Entry DOI | 10.2210/pdb7af1/pdb |
Related | 6TT5 |
Descriptor | Protein artemis, 1,2-ETHANEDIOL, ZINC ION, ... (4 entities in total) |
Functional Keywords | artemis, snm1c, dclre1c, nuclease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 42465.85 |
Authors | Yosaatmadja, Y.,Goubin, S.,Newman, J.A.,Mukhopadhyay, S.M.M.,Dannerfjord, A.A.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Bountra, C.,Gileadi, O. (deposition date: 2020-09-19, release date: 2020-10-28, Last modification date: 2024-01-31) |
Primary citation | Yosaatmadja, Y.,Baddock, H.T.,Newman, J.A.,Bielinski, M.,Gavard, A.E.,Mukhopadhyay, S.M.M.,Dannerfjord, A.A.,Schofield, C.J.,McHugh, P.J.,Gileadi, O. Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition. Nucleic Acids Res., 49:9310-9326, 2021 Cited by PubMed: 34387696DOI: 10.1093/nar/gkab693 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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