7A29
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation
Summary for 7A29
Entry DOI | 10.2210/pdb7a29/pdb |
EMDB information | 11617 |
Descriptor | Spike glycoprotein, Neutralising sybody (Sb23), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | sars-cov-2, complex, nanobody, spike, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 478146.38 |
Authors | Hallberg, B.M.,Das, H. (deposition date: 2020-08-16, release date: 2020-10-21, Last modification date: 2020-11-18) |
Primary citation | Custodio, T.F.,Das, H.,Sheward, D.J.,Hanke, L.,Pazicky, S.,Pieprzyk, J.,Sorgenfrei, M.,Schroer, M.A.,Gruzinov, A.Y.,Jeffries, C.M.,Graewert, M.A.,Svergun, D.I.,Dobrev, N.,Remans, K.,Seeger, M.A.,McInerney, G.M.,Murrell, B.,Hallberg, B.M.,Low, C. Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11:5588-5588, 2020 Cited by PubMed: 33149112DOI: 10.1038/s41467-020-19204-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.94 Å) |
Structure validation
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