7A1J
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II) AND 3-(3-phenylpropyl)-2-oxoglutarate
Summary for 7A1J
Entry DOI | 10.2210/pdb7a1j/pdb |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hypoxia-inducible factor asparagine hydroxylase, dioxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41138.28 |
Authors | Nakashima, Y.,Brewitz, L.,Schofield, C.J. (deposition date: 2020-08-13, release date: 2021-08-25, Last modification date: 2024-01-31) |
Primary citation | Nakashima, Y.,Brewitz, L.,Tumber, A.,Salah, E.,Schofield, C.J. 2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases. Nat Commun, 12:6478-6478, 2021 Cited by PubMed: 34759269DOI: 10.1038/s41467-021-26673-2 PDB entries with the same primary citation |
Experimental method |
Structure validation
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