7A0N

Structure of TSC1 NTD and linker domain

Summary for 7A0N

• Entry DOI: 10.2210/pdb7a0n/pdb
• Descriptor: Uncharacterized protein,Uncharacterized protein (1 entity in total)
• Functional Keywords: tsc1, gap, gtpase, signaling protein
• Biological source: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719); More
• Total number of polymer chains: 4
• Total formula weight: 217811.53

Authors

Fitzian, K.,Kuemmel, D. (deposition date: 2020-08-10, release date: 2021-05-26, Last modification date: 2024-01-31)

• Primary citation: Fitzian, K.,Bruckner, A.,Brohee, L.,Zech, R.,Antoni, C.,Kiontke, S.,Gasper, R.,Linard Matos, A.L.,Beel, S.,Wilhelm, S.,Gerke, V.,Ungermann, C.,Nellist, M.,Raunser, S.,Demetriades, C.,Oeckinghaus, A.,Kummel, D.; TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.; Mol.Cell, 81:2705-, 2021; PubMed: 33974911; DOI: 10.1016/j.molcel.2021.04.019

Experimental method

X-RAY DIFFRACTION (4.3 Å)