6ZZQ

Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Acinetobacter baumannii complexed with NAD+ and acetoacetate

Summary for 6ZZQ

Entry DOI	10.2210/pdb6zzq/pdb
Descriptor	3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ACETOACETIC ACID, ... (4 entities in total)
Functional Keywords	(r)-3-hydroxybutyrate dehydrogenase, short-chain dehydrogenase/reductase, mesophilic enzyme, oxidoreductase
Biological source	Acinetobacter baumannii
Total number of polymer chains	1
Total formula weight	28435.42
Authors	Machado, T.F.G.,da Silva, R.G.,Gloster, T.M.,McMahon, S.A.,Oehler, V. (deposition date: 2020-08-05, release date: 2020-10-07, Last modification date: 2024-01-31)
Primary citation	Machado, T.F.G.,Purg, M.,McMahon, S.A.,Read, B.J.,Oehler, V.,Aqvist, J.,Gloster, T.M.,da Silva, R.G. Dissecting the Mechanism of ( R )-3-Hydroxybutyrate Dehydrogenase by Kinetic Isotope Effects, Protein Crystallography, and Computational Chemistry. Acs Catalysis, 10:15019-15032, 2020 Cited by PubMed: 33391858 DOI: 10.1021/acscatal.0c04736 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation