6ZZQ

Crystal structure of (R)-3-hydroxybutyrate dehydrogenase from Acinetobacter baumannii complexed with NAD+ and acetoacetate

6ZZQ の概要

• エントリーDOI: 10.2210/pdb6zzq/pdb
• 分子名称: 3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ACETOACETIC ACID, ... (4 entities in total)
• 機能のキーワード: (r)-3-hydroxybutyrate dehydrogenase, short-chain dehydrogenase/reductase, mesophilic enzyme, oxidoreductase
• 由来する生物種: Acinetobacter baumannii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28435.42

構造登録者

Machado, T.F.G.,da Silva, R.G.,Gloster, T.M.,McMahon, S.A.,Oehler, V. (登録日: 2020-08-05, 公開日: 2020-10-07, 最終更新日: 2024-01-31)

• 主引用文献: Machado, T.F.G.,Purg, M.,McMahon, S.A.,Read, B.J.,Oehler, V.,Aqvist, J.,Gloster, T.M.,da Silva, R.G.; Dissecting the Mechanism of ( R )-3-Hydroxybutyrate Dehydrogenase by Kinetic Isotope Effects, Protein Crystallography, and Computational Chemistry.; Acs Catalysis, 10:15019-15032, 2020; PubMed: 33391858; DOI: 10.1021/acscatal.0c04736

実験手法

X-RAY DIFFRACTION (1.93 Å)