6ZTI

Phospholipase PlaB from Legionella pneumophila in complex with thio-NAD

Summary for 6ZTI

Entry DOI	10.2210/pdb6zti/pdb
Descriptor	PlaB phospholipase, THIONICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
Functional Keywords	phospholipase, alpha/beta hydrolase, virulence, infectious disease, hydrolase
Biological source	Legionella pneumophila
Total number of polymer chains	4
Total formula weight	227351.96
Authors	Diwo, M.G.,Flieger, A.,Blankenfeldt, W. (deposition date: 2020-07-20, release date: 2021-06-02, Last modification date: 2024-05-15)
Primary citation	Diwo, M.,Michel, W.,Aurass, P.,Kuhle-Keindorf, K.,Pippel, J.,Krausze, J.,Wamp, S.,Lang, C.,Blankenfeldt, W.,Flieger, A. NAD(H)-mediated tetramerization controls the activity of Legionella pneumophila phospholipase PlaB. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34074754 DOI: 10.1073/pnas.2017046118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation