6ZP0

Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State

6ZP0 の概要

• エントリーDOI: 10.2210/pdb6zp0/pdb
• EMDBエントリー: 11332
• 分子名称: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: coronavirus, sars-cov-2, spike protein, s protein, s antigen, covid-19, receptor binding, membrane fusion, vaccine design, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 427995.02

構造登録者

Xiong, X.,Qu, K.,Scheres, S.H.W.,Briggs, J.A.G. (登録日: 2020-07-08, 公開日: 2020-07-22, 最終更新日: 2021-06-02)

• 主引用文献: Xiong, X.,Qu, K.,Ciazynska, K.A.,Hosmillo, M.,Carter, A.P.,Ebrahimi, S.,Ke, Z.,Scheres, S.H.W.,Bergamaschi, L.,Grice, G.L.,Zhang, Y.,Nathan, J.A.,Baker, S.,James, L.C.,Baxendale, H.E.,Goodfellow, I.,Doffinger, R.,Briggs, J.A.G.; A thermostable, closed SARS-CoV-2 spike protein trimer.; Nat.Struct.Mol.Biol., 27:934-941, 2020; PubMed: 32737467; DOI: 10.1038/s41594-020-0478-5

実験手法

ELECTRON MICROSCOPY (3 Å)