6ZHZ

OleP-oleandolide(DEO) in high salt crystallization conditions

Summary for 6ZHZ

Entry DOI	10.2210/pdb6zhz/pdb
Descriptor	Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE, (3~{R},4~{S},5~{R},6~{S},7~{S},9~{S},11~{R},12~{S},13~{R},14~{R})-3,5,7,9,11,13,14-heptamethyl-4,6,12-tris(oxidanyl)-1-oxacyclotetradecane-2,10-dione, ... (8 entities in total)
Functional Keywords	cytochrome p450, 8.8a-deoxyoleandolide monooxygenase, 8.8a-deoxyoleandolide, oxidoreductase
Biological source	Streptomyces antibioticus
Total number of polymer chains	6
Total formula weight	281689.18
Authors	Montemiglio, L.C.,Savino, C.,Vallone, B.,Parisi, G.,Cecchetti, C. (deposition date: 2020-06-24, release date: 2020-10-21, Last modification date: 2024-01-24)
Primary citation	Parisi, G.,Freda, I.,Exertier, C.,Cecchetti, C.,Gugole, E.,Cerutti, G.,D'Auria, L.,Macone, A.,Vallone, B.,Savino, C.,Montemiglio, L.C. Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate. Biomolecules, 10:-, 2020 Cited by PubMed: 33036250 DOI: 10.3390/biom10101411 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation