6ZH6
Cryo-EM structure of DNA-PKcs:Ku80ct194
Summary for 6ZH6
Entry DOI | 10.2210/pdb6zh6/pdb |
EMDB information | 11215 |
Descriptor | DNA-dependent protein kinase catalytic subunit,DNA-PKcs, X-ray repair cross-complementing protein 5 (2 entities in total) |
Functional Keywords | kinase, dna-pkcs, nhej, dna-repair, dna-pk, dna binding protein, ku80 |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 493511.16 |
Authors | Chaplin, A.K.,Hardwick, S.W.,Chirgadze, D.Y.,Blundell, T.L. (deposition date: 2020-06-21, release date: 2020-10-21, Last modification date: 2024-05-01) |
Primary citation | Chaplin, A.K.,Hardwick, S.W.,Liang, S.,Kefala Stavridi, A.,Hnizda, A.,Cooper, L.R.,De Oliveira, T.M.,Chirgadze, D.Y.,Blundell, T.L. Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28:13-19, 2021 Cited by PubMed: 33077952DOI: 10.1038/s41594-020-00517-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.93 Å) |
Structure validation
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