6ZGB

glutamate transporter homologue Glttk in complex with a photo cage compound

Summary for 6ZGB

Entry DOI	10.2210/pdb6zgb/pdb
Descriptor	Proton/glutamate symporter, SDF family, (2~{S},3~{S})-2-azanyl-3-[(2-nitrophenyl)methoxy]butanedioic acid, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywords	glutamate transporter, photo cage, membrane protein, transport protein
Biological source	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Total number of polymer chains	3
Total formula weight	141483.41
Authors	Arkhipova, V.,Slotboom, D.J.,Guskov, A. (deposition date: 2020-06-18, release date: 2021-01-27, Last modification date: 2024-01-24)
Primary citation	Arkhipova, V.,Fu, H.,Hoorens, M.W.H.,Trinco, G.,Lameijer, L.N.,Marin, E.,Feringa, B.L.,Poelarends, G.J.,Szymanski, W.,Slotboom, D.J.,Guskov, A. Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143:1513-1520, 2021 Cited by PubMed: 33449695 DOI: 10.1021/jacs.0c11336 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation