6ZFT

Crystal structure of bovine cytochrome bc1 in complex with quinolone inhibitor CK-2-68

Summary for 6ZFT

• Entry DOI: 10.2210/pdb6zft/pdb
• Descriptor: Cytochrome b-c1 complex subunit 1, mitochondrial, Cytochrome b-c1 complex subunit 9, TETRAETHYLENE GLYCOL, ... (22 entities in total)
• Functional Keywords: cytochrome bc1, malaria, electron transport
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 10
• Total formula weight: 238331.55

Authors

Amporndanai, K.,O'Neill, P.M.,Hong, W.D.,Amewu, R.K.,Pidathala, C.,Berry, N.G.,Biagini, G.A.,Leung, S.C.,Hasnain, S.S.,Antonyuk, S.V. (deposition date: 2020-06-17, release date: 2021-06-30, Last modification date: 2024-01-24)

• Primary citation: Amporndanai, K.,O'Neill, P.M.,Hong, W.D.,Amewu, R.K.,Pidathala, C.,Berry, N.,Biangini, G.A.,Leung, S.C.,Hasnain, S.S.,Antonyuk, S.V.; Targeting the ubiquinol-reduction (Qi) site of the mitochondrial cytochrome bc1 complex for the development of next generation quinolone antimalarials; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.3 Å)