6ZCC
X-ray structure of the Haloalkane dehalogenase HOB (HaloTag7-based Oligonucleotide Binder) labeled with a chloroalkane-tetramethylrhodamine fluorophore substrate
Summary for 6ZCC
Entry DOI | 10.2210/pdb6zcc/pdb |
Related | 6Y7A 6Y7B |
Descriptor | Haloalkane dehalogenase, [9-[2-carboxy-5-[2-[2-(6-chloranylhexoxy)ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium, ACETATE ION, ... (5 entities in total) |
Functional Keywords | haloalkane dehalogenase, halo, tag, halotag7, self-labeling protein, (synthetic) fluorophore, tetramethylrhodamine, oligonucleotide binder, hydrolase |
Biological source | Rhodococcus sp. |
Total number of polymer chains | 1 |
Total formula weight | 34268.95 |
Authors | Tarnawski, M.,Johnsson, K.,Hiblot, J. (deposition date: 2020-06-10, release date: 2021-04-21, Last modification date: 2024-01-24) |
Primary citation | Wilhelm, J.,Kuhn, S.,Tarnawski, M.,Gotthard, G.,Tunnermann, J.,Tanzer, T.,Karpenko, J.,Mertes, N.,Xue, L.,Uhrig, U.,Reinstein, J.,Hiblot, J.,Johnsson, K. Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60:2560-2575, 2021 Cited by PubMed: 34339177DOI: 10.1021/acs.biochem.1c00258 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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