6ZBK

Crystal structure of the human complex between RPAP3 and TRBP

Summary for 6ZBK

• Entry DOI: 10.2210/pdb6zbk/pdb
• Descriptor: RNA polymerase II-associated protein 3, RISC-loading complex subunit TARBP2 (3 entities in total)
• Functional Keywords: rnps, micrornas, rna induced silencing complex, dsrna pathways, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 25664.17

Authors

Charron, C.,Abel, Y.,Charpentier, B.,Rederstorff, M. (deposition date: 2020-06-08, release date: 2021-06-30, Last modification date: 2024-01-24)

• Primary citation: Abel, Y.,Charron, C.,Virciglio, C.,Bourguignon-Igel, V.,Quinternet, M.,Chagot, M.E.,Robert, M.C.,Verheggen, C.,Branlant, C.,Bertrand, E.,Manival, X.,Charpentier, B.,Rederstorff, M.; The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.; Nucleic Acids Res., 50:2172-2189, 2022; PubMed: 35150569; DOI: 10.1093/nar/gkac086

Experimental method

X-RAY DIFFRACTION (1.49 Å)