6Z5B

Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003128

Summary for 6Z5B

• Entry DOI: 10.2210/pdb6z5b/pdb
• Descriptor: Serine/threonine-protein kinase haspin, DIMETHYL SULFOXIDE, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... (4 entities in total)
• Functional Keywords: kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 41322.27

Authors

Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003128; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)