6Z59
Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003816
Summary for 6Z59
Entry DOI | 10.2210/pdb6z59/pdb |
Descriptor | Serine/threonine-protein kinase haspin, 11-oxa-8,14,18,19,22-pentazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2,4,6(23),15(22),16,19-heptaen-7-one, SODIUM ION, ... (4 entities in total) |
Functional Keywords | kinase, kinase inhibitor, haspin, gsg2 macrocycle, nanocyclic, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41057.82 |
Authors | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-05-26, release date: 2020-06-03, Last modification date: 2024-01-24) |
Primary citation | Chaikuad, A.,Benderitter, P.,Hoflack, J.,Denis, A.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of haspin (GSG2) in complex with macrocycle ODS2003816 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report