6Z2E

Crystal structure of SARS-CoV-2 Mpro in complex with the activity-based probe, biotin-PEG(4)-Abu-Tle-Leu-Gln-vinylsulfone

これはPDB形式変換不可エントリーです。

6Z2E の概要

• エントリーDOI: 10.2210/pdb6z2e/pdb
• 分子名称: 3C-like proteinase, (4~{S})-4-[[(2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-[3-[2-[2-[2-[2-[5-[(3~{a}~{S},4~{R},6~{a}~{R})-2-oxidanylidene-3,3~{a},4,6~{a}-tetrahydro-1~{H}-thieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]butanoyl]amino]-3,3-dimethyl-butanoyl]amino]-4-methyl-pentanoyl]amino]-6-methylsulfonyl-hexanamide, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, main protease, activity-based probe, inhibitor, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34912.72

構造登録者

Zhang, L.,Hilgenfeld, R. (登録日: 2020-05-15, 公開日: 2020-06-17, 最終更新日: 2024-01-24)

• 主引用文献: Zhang, L.,Hilgenfeld, R.; Crystal structure of SARS-CoV-2 Mpro in complex with the activity-based probe, biotin-PEG(4)-Abu-Tle-Leu-Gln-vinylsulfone; To Be Published,

実験手法

X-RAY DIFFRACTION (1.7 Å)