6YYW

Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 2-oxoglutarate, and factor X substrate peptide fragment(39mer-4Ser)

6YYW の概要

• エントリーDOI: 10.2210/pdb6yyw/pdb
• 分子名称: Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53796.76

構造登録者

Nakashima, Y.,Brewitz, L.,Schofield, C.J. (登録日: 2020-05-06, 公開日: 2021-03-17, 最終更新日: 2024-02-07)

• 主引用文献: Brewitz, L.,Nakashima, Y.,Schofield, C.J.; Synthesis of 2-oxoglutarate derivatives and their evaluation as cosubstrates and inhibitors of human aspartate/asparagine-beta-hydroxylase.; Chem Sci, 12:1327-1342, 2020; PubMed: 34163896; DOI: 10.1039/d0sc04301j

実験手法

X-RAY DIFFRACTION (2.27 Å)