6YEM
H1N1 2009 PA Endonuclease in complex with Quambalarine B
Summary for 6YEM
| Entry DOI | 10.2210/pdb6yem/pdb |
| Descriptor | Polymerase acidic protein,Polymerase acidic protein, MANGANESE (II) ION, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | influenza, polymerase, endonuclease, hydrolase, viral protein |
| Biological source | Influenza A virus (A/California/07/2009(H1N1)) More |
| Total number of polymer chains | 1 |
| Total formula weight | 22116.47 |
| Authors | Radilova, K.,Brynda, J. (deposition date: 2020-03-25, release date: 2020-09-09, Last modification date: 2024-01-24) |
| Primary citation | Zima, V.,Radilova, K.,Kozisek, M.,Albinana, C.B.,Karlukova, E.,Brynda, J.,Fanfrlik, J.,Flieger, M.,Hodek, J.,Weber, J.,Majer, P.,Konvalinka, J.,Machara, A. Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. Eur.J.Med.Chem., 208:112754-112754, 2020 Cited by PubMed: 32883638DOI: 10.1016/j.ejmech.2020.112754 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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