6YEM

H1N1 2009 PA Endonuclease in complex with Quambalarine B

6YEM の概要

• エントリーDOI: 10.2210/pdb6yem/pdb
• 分子名称: Polymerase acidic protein,Polymerase acidic protein, MANGANESE (II) ION, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: influenza, polymerase, endonuclease, hydrolase, viral protein
• 由来する生物種: Influenza A virus (A/California/07/2009(H1N1)); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22116.47

構造登録者

Radilova, K.,Brynda, J. (登録日: 2020-03-25, 公開日: 2020-09-09, 最終更新日: 2024-01-24)

• 主引用文献: Zima, V.,Radilova, K.,Kozisek, M.,Albinana, C.B.,Karlukova, E.,Brynda, J.,Fanfrlik, J.,Flieger, M.,Hodek, J.,Weber, J.,Majer, P.,Konvalinka, J.,Machara, A.; Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors.; Eur.J.Med.Chem., 208:112754-112754, 2020; PubMed: 32883638; DOI: 10.1016/j.ejmech.2020.112754

実験手法

X-RAY DIFFRACTION (2.5 Å)