6YD1
SaFtsZ-DFMBA
Summary for 6YD1
Entry DOI | 10.2210/pdb6yd1/pdb |
Descriptor | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 2,6-difluoro-3-methoxybenzamide, ... (5 entities in total) |
Functional Keywords | cell division protein, cell cycle |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 32407.38 |
Authors | Fernandez-Tornero, C.,Ruiz, F.M.,Andreu, J.M. (deposition date: 2020-03-20, release date: 2021-07-28, Last modification date: 2024-01-24) |
Primary citation | Huecas, S.,Araujo-Bazan, L.,Ruiz, F.M.,Ruiz-Avila, L.B.,Martinez, R.F.,Escobar-Pena, A.,Artola, M.,Vazquez-Villa, H.,Martin-Fontecha, M.,Fernandez-Tornero, C.,Lopez-Rodriguez, M.L.,Andreu, J.M. Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery. J.Med.Chem., 64:5730-5745, 2021 Cited by PubMed: 33908781DOI: 10.1021/acs.jmedchem.0c02207 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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