6XZH

Structure of zVDR LBD-Calcitriol in complex with chimera 10

6XZH の概要

• エントリーDOI: 10.2210/pdb6xzh/pdb
• 分子名称: Vitamin D3 receptor A, ARG-HIS-LYS-ILE-URL-URK-URL-LEU-GLN, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, foldamer, helix mimicry, protein-protein interaction, gene regulation
• 由来する生物種: Danio rerio (Zebrafish); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35716.91

構造登録者

Buratto, J.,Belorusova, A.Y.,Rochel, N.,Guichard, G. (登録日: 2020-02-04, 公開日: 2021-02-17, 最終更新日: 2024-01-24)

• 主引用文献: Cussol, L.,Mauran-Ambrosino, L.,Buratto, J.,Belorusova, A.Y.,Neuville, M.,Osz, J.,Fribourg, S.,Fremaux, J.,Dolain, C.,Goudreau, S.R.,Rochel, N.,Guichard, G.; Structural Basis for alpha-Helix Mimicry and Inhibition of Protein-Protein Interactions with Oligourea Foldamers.; Angew.Chem.Int.Ed.Engl., 60:2296-2303, 2021; PubMed: 32935897; DOI: 10.1002/anie.202008992

実験手法

X-RAY DIFFRACTION (2.372 Å)