6XX5
Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin
6XX5 の概要
エントリーDOI | 10.2210/pdb6xx5/pdb |
関連するBIRD辞書のPRD_ID | PRD_900086 |
分子名称 | Proto-oncogene tyrosine-protein kinase Src, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, ... (4 entities in total) |
機能のキーワード | beta barrel, sh3 domain, protein binding |
由来する生物種 | Gallus gallus (Chicken) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 8235.47 |
構造登録者 | |
主引用文献 | Plaza-Garrido, M.,Salinas-Garcia, M.C.,Martinez, J.C.,Camara-Artigas, A. The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25:621-634, 2020 Cited by PubMed: 32279137DOI: 10.1007/s00775-020-01785-0 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.3 Å) |
構造検証レポート
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