6XQR
OXA-48 bound by Compound 2.2
Summary for 6XQR
Entry DOI | 10.2210/pdb6xqr/pdb |
Descriptor | Beta-lactamase, [1,1'-biphenyl]-4,4'-disulfonic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | beta-lactamase, carbapenemase, beta-lactamase inhibitor, complex, oxacillinase, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 2 |
Total formula weight | 57254.23 |
Authors | Taylor, D.M.,Hu, L.,Prasad, B.V.V.,Palzkill, T. (deposition date: 2020-07-10, release date: 2021-12-15, Last modification date: 2023-11-15) |
Primary citation | Taylor, D.M.,Anglin, J.,Hu, L.,Wang, L.,Sankaran, B.,Wang, J.,Matzuk, M.M.,Prasad, B.V.V.,Palzkill, T. Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7:3345-3354, 2021 Cited by PubMed: 34817169DOI: 10.1021/acsinfecdis.1c00501 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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