6XI9

X-ray crystal structure of MqnE from Pedobacter heparinus in complex with aminofutalosine and methionine

6XI9 の概要

• エントリーDOI: 10.2210/pdb6xi9/pdb
• 分子名称: Aminodeoxyfutalosine synthase, IRON/SULFUR CLUSTER, METHIONINE, ... (6 entities in total)
• 機能のキーワード: iron-sulfur cluster, radical sam, menaquinone biosynthesis, biosynthetic protein
• 由来する生物種: Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99614.42

構造登録者

Grove, T.L.,Bonanno, J.B.,Almo, S.C. (登録日: 2020-06-19, 公開日: 2020-07-15, 最終更新日: 2024-03-06)

• 主引用文献: Carl, A.G.,Harris, L.D.,Feng, M.,Nordstrom, L.U.,Gerfen, G.J.,Evans, G.B.,Silakov, A.,Almo, S.C.,Grove, T.L.; Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis.; Biochemistry, 59:2562-2575, 2020; PubMed: 32627538; DOI: 10.1021/acs.biochem.0c00070

実験手法

X-RAY DIFFRACTION (2.14 Å)