6XHU

Room temperature X-ray crystallography reveals oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: Insights for enzyme mechanism and drug design

6XHU の概要

• エントリーDOI: 10.2210/pdb6xhu/pdb
• 分子名称: 3C-like proteinase (2 entities in total)
• 機能のキーワード: sars-cov2 main protease, viral protein, hydrolase
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67651.09

構造登録者

Kneller, D.W.,Coates, L.,Kovalevsky, A. (登録日: 2020-06-19, 公開日: 2020-07-01, 最終更新日: 2023-10-18)

• 主引用文献: Kneller, D.W.,Phillips, G.,O'Neill, H.M.,Tan, K.,Joachimiak, A.,Coates, L.,Kovalevsky, A.; Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL M pro : insights into enzyme mechanism and drug design.; Iucrj, 7:-, 2020; PubMed: 33063790; DOI: 10.1107/S2052252520012634

実験手法

X-RAY DIFFRACTION (1.8 Å)