6XFI

Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies

Summary for 6XFI

• Entry DOI: 10.2210/pdb6xfi/pdb
• Descriptor: Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: muscular dystrophy, alpha-dystroglycan, o-mannosylation, pomgnt2, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 61877.76

Authors

Halmo, S.M.,Yeh, J.,Wells, L.,Moremen, K.W.,Lanzilotta, W.N. (deposition date: 2020-06-15, release date: 2021-04-21)

• Primary citation: Yang, J.Y.,Halmo, S.M.,Praissman, J.,Chapla, D.,Singh, D.,Wells, L.,Moremen, K.W.,Lanzilotta, W.N.; Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.; Acta Crystallogr D Struct Biol, 77:486-495, 2021; PubMed: 33825709; DOI: 10.1107/S2059798321001261

Experimental method

X-RAY DIFFRACTION (2 Å)