6XFI

Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for Inherited Muscular Dystrophies

6XFI の概要

• エントリーDOI: 10.2210/pdb6xfi/pdb
• 分子名称: Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2, URIDINE-5'-DIPHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: muscular dystrophy, alpha-dystroglycan, o-mannosylation, pomgnt2, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 61877.76

構造登録者

Halmo, S.M.,Yeh, J.,Wells, L.,Moremen, K.W.,Lanzilotta, W.N. (登録日: 2020-06-15, 公開日: 2021-04-21)

• 主引用文献: Yang, J.Y.,Halmo, S.M.,Praissman, J.,Chapla, D.,Singh, D.,Wells, L.,Moremen, K.W.,Lanzilotta, W.N.; Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2: structural basis for inherited muscular dystrophies.; Acta Crystallogr D Struct Biol, 77:486-495, 2021; PubMed: 33825709; DOI: 10.1107/S2059798321001261

実験手法

X-RAY DIFFRACTION (2 Å)