6XA1

Structure of a drug-like compound stalled human translation termination complex

This is a non-PDB format compatible entry.

Summary for 6XA1

• Entry DOI: 10.2210/pdb6xa1/pdb
• EMDB information: 22085
• Descriptor: 60S ribosomal protein L8, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (87 entities in total)
• Functional Keywords: selectively stalling, translation termination, drug-like compound, human ribosome, ribosome
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 83
• Total formula weight: 3134503.88

Authors

Li, W.,Cate, J. (deposition date: 2020-06-03, release date: 2020-10-07, Last modification date: 2020-10-14)

• Primary citation: Li, W.,Chang, S.T.,Ward, F.R.,Cate, J.H.D.; Selective inhibition of human translation termination by a drug-like compound.; Nat Commun, 11:4941-4941, 2020; PubMed: 33009412; DOI: 10.1038/s41467-020-18765-2

Experimental method

ELECTRON MICROSCOPY (2.8 Å)