6X7L
LnmK in complex with 2-nitronate-propionyl-CoA
6X7L の概要
エントリーDOI | 10.2210/pdb6x7l/pdb |
分子名称 | Bifunctional methylmalonyl-CoA:ACP acyltransferase/decarboxylase, ALANINE, [1-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethylsulfanyl]-1-oxidanylidene-propan-2-ylidene]-bis(oxidanidyl)azanium, ... (5 entities in total) |
機能のキーワード | transferase, lyase, inhibitor, isostere, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
由来する生物種 | Streptomyces atroolivaceus |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 36913.44 |
構造登録者 | |
主引用文献 | Stunkard, L.M.,Kick, B.J.,Lohman, J.R. Structures of LnmK, a Bifunctional Acyltransferase/Decarboxylase, with Substrate Analogues Reveal the Basis for Selectivity and Stereospecificity. Biochemistry, 60:365-372, 2021 Cited by PubMed: 33482062DOI: 10.1021/acs.biochem.0c00893 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.77 Å) |
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