6X1H

Crystal structure of a guanine nucleotide exchange factor (GEF) domain from the Orientia tsutsugamushi protein OtDUB

Summary for 6X1H

Entry DOI	10.2210/pdb6x1h/pdb
Descriptor	ULP_PROTEASE domain-containing protein, NICKEL (II) ION (3 entities in total)
Functional Keywords	guanine nucleotide exchange factor, gef, orientia tsutsugamushi, scrub typhus, signaling protein
Biological source	Orientia tsutsugamushi (Rickettsia tsutsugamushi)
Total number of polymer chains	6
Total formula weight	151201.88
Authors	Lim, C.S.,Xiong, Y. (deposition date: 2020-05-18, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Lim, C.,Berk, J.M.,Blaise, A.,Bircher, J.,Koleske, A.J.,Hochstrasser, M.,Xiong, Y. Crystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi . Proc.Natl.Acad.Sci.USA, 117:30380-30390, 2020 Cited by PubMed: 33184172 DOI: 10.1073/pnas.2018163117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.91 Å)

Structure validation