6WYP
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 1 (CD1) K330L mutant complexed with SAHA-BPyne
Summary for 6WYP
Entry DOI | 10.2210/pdb6wyp/pdb |
Descriptor | Histone deacetylase 6, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | histone deacetylase, hydrolase, metalloprotein |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 42657.76 |
Authors | Osko, J.D.,Christianson, D.W. (deposition date: 2020-05-13, release date: 2020-09-02, Last modification date: 2023-10-18) |
Primary citation | Osko, J.D.,Christianson, D.W. Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6. Acta Crystallogr.,Sect.F, 76:428-437, 2020 Cited by PubMed: 32880591DOI: 10.1107/S2053230X20010250 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.40006356531 Å) |
Structure validation
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