6WVS
Hyperstable de novo TIM barrel variant DeNovoTIM15
Summary for 6WVS
| Entry DOI | 10.2210/pdb6wvs/pdb |
| Descriptor | DeNovoTIM15 hyperstable de novo TIM barrel (2 entities in total) |
| Functional Keywords | tim barrel, hyperstable, symmetric, de novo, repeat protein, de novo protein |
| Biological source | synthetic construct |
| Total number of polymer chains | 1 |
| Total formula weight | 21824.44 |
| Authors | Bick, M.J.,Haydon, I.C.,Caldwell, S.J.,Zeymer, C.,Huang, P.,Fernandez-Velasco, D.A.,Baker, D. (deposition date: 2020-05-06, release date: 2020-11-25, Last modification date: 2024-04-03) |
| Primary citation | Caldwell, S.J.,Haydon, I.C.,Piperidou, N.,Huang, P.S.,Bick, M.J.,Sjostrom, H.S.,Hilvert, D.,Baker, D.,Zeymer, C. Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117:30362-30369, 2020 Cited by PubMed: 33203677DOI: 10.1073/pnas.2008535117 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.202 Å) |
Structure validation
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