6WVS

Hyperstable de novo TIM barrel variant DeNovoTIM15

6WVS の概要

• エントリーDOI: 10.2210/pdb6wvs/pdb
• 分子名称: DeNovoTIM15 hyperstable de novo TIM barrel (2 entities in total)
• 機能のキーワード: tim barrel, hyperstable, symmetric, de novo, repeat protein, de novo protein
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21824.44

構造登録者

Bick, M.J.,Haydon, I.C.,Caldwell, S.J.,Zeymer, C.,Huang, P.,Fernandez-Velasco, D.A.,Baker, D. (登録日: 2020-05-06, 公開日: 2020-11-25, 最終更新日: 2024-04-03)

• 主引用文献: Caldwell, S.J.,Haydon, I.C.,Piperidou, N.,Huang, P.S.,Bick, M.J.,Sjostrom, H.S.,Hilvert, D.,Baker, D.,Zeymer, C.; Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.; Proc.Natl.Acad.Sci.USA, 117:30362-30369, 2020; PubMed: 33203677; DOI: 10.1073/pnas.2008535117

実験手法

X-RAY DIFFRACTION (2.202 Å)