6WS3
The crystal structure of the 2009/H1N1/California PA endonuclease wild type bound to DNA oligomers TG and AGCA (from cleaved GTGAGCAGTG)
Summary for 6WS3
| Entry DOI | 10.2210/pdb6ws3/pdb |
| Related | 6WHM |
| Descriptor | Protein PA-X,Polymerase acidic protein, DNA (5'-D(P*TP*G)-3'), GLYCEROL, ... (6 entities in total) |
| Functional Keywords | nuclease, influenza, dna oligomer, cleaved, viral protein, viral protein-dna complex, dna binding protein, viral protein/dna |
| Biological source | Influenza A virus More |
| Total number of polymer chains | 3 |
| Total formula weight | 29829.70 |
| Authors | Cuypers, M.G.,Kumar, G.,Webb, T.,White, S.W. (deposition date: 2020-04-30, release date: 2021-02-03, Last modification date: 2023-10-18) |
| Primary citation | Kumar, G.,Cuypers, M.,Webby, R.R.,Webb, T.R.,White, S.W. Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism. Nucleic Acids Res., 49:1609-1618, 2021 Cited by PubMed: 33469660DOI: 10.1093/nar/gkaa1294 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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