6WN0

The structure of a CoA-dependent acyl-homoserine lactone synthase, RpaI, with the adduct of SAH and p-coumaroyl CoA

Summary for 6WN0

• Entry DOI: 10.2210/pdb6wn0/pdb
• Descriptor: 4-coumaroyl-homoserine lactone synthase, COENZYME A, (2S)-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)-2-{[(2E)-3-(cis-4-hydroxycyclohexa-2,5-dien-1-yl)prop-2-enoyl]amino}butanoic acid, ... (4 entities in total)
• Functional Keywords: acyl-homoserine lactone, coenzyme a, rpai, transferase
• Biological source: Rhodopseudomonas palustris
• Total number of polymer chains: 2
• Total formula weight: 50803.26

Authors

Dong, S.-H.,Nair, S.K. (deposition date: 2020-04-22, release date: 2020-05-13, Last modification date: 2023-10-18)

• Primary citation: Dong, S.H.,Nhu-Lam, M.,Nagarajan, R.,Nair, S.K.; Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities.; Acs Chem.Biol., 15:1497-1504, 2020; PubMed: 32356962; DOI: 10.1021/acschembio.0c00142

Experimental method

X-RAY DIFFRACTION (1.85 Å)