6WMB

Crystal structure of a soluble variant of full-length human APOBEC3G (pH 8.0)

6WMB の概要

• エントリーDOI: 10.2210/pdb6wmb/pdb
• 分子名称: APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G, DNA (5'-D(P*CP*C)-3'), ZINC ION, ... (4 entities in total)
• 機能のキーワード: apobec3g, antiviral defense, hydrolase, dna cytidine deaminase, hydrolase-dna complex, hydrolase/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43066.53

構造登録者

Maiti, A.,Matsuo, H. (登録日: 2020-04-21, 公開日: 2020-12-23, 最終更新日: 2023-10-18)

• 主引用文献: Maiti, A.,Myint, W.,Delviks-Frankenberry, K.A.,Hou, S.,Kanai, T.,Balachandran, V.,Sierra Rodriguez, C.,Tripathi, R.,Kurt Yilmaz, N.,Pathak, V.K.,Schiffer, C.A.,Matsuo, H.; Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains.; J.Mol.Biol., 432:6042-6060, 2020; PubMed: 33098858; DOI: 10.1016/j.jmb.2020.10.020

実験手法

X-RAY DIFFRACTION (3.02 Å)