6WL3
preTCRbeta-pMHC complex crystal structure
Summary for 6WL3
Entry DOI | 10.2210/pdb6wl3/pdb |
Descriptor | H-2 class I histocompatibility antigen, K-B alpha chain, ARG-GLY-TYR-LEU-TYR-GLN-GLY-LEU, N15 preTCR beta (3 entities in total) |
Functional Keywords | pretcr, h-2kb, t cell development, beta selection, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 9 |
Total formula weight | 149221.19 |
Authors | Li, X.,Mallis, R.J.,Mizsei, R.,Tan, K.,Reinherz, E.L.,Wang, J. (deposition date: 2020-04-18, release date: 2020-12-23, Last modification date: 2023-10-18) |
Primary citation | Li, X.,Mizsei, R.,Tan, K.,Mallis, R.J.,Duke-Cohan, J.S.,Akitsu, A.,Tetteh, P.W.,Dubey, A.,Hwang, W.,Wagner, G.,Lang, M.J.,Arthanari, H.,Wang, J.H.,Reinherz, E.L. Pre-T cell receptors topologically sample self-ligands during thymocyte beta-selection. Science, 371:181-185, 2021 Cited by PubMed: 33335016DOI: 10.1126/science.abe0918 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.45 Å) |
Structure validation
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