6WKM

Fab Fragment of Anti-human LAG3 antibody (22D2)

Summary for 6WKM

• Entry DOI: 10.2210/pdb6wkm/pdb
• Descriptor: 22D2 Fab Heavy Chain, 22D2 Fab Light Chain (3 entities in total)
• Functional Keywords: anti human lag3, immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 48977.37

Authors

Agnihotri, P.,Mishra, A.K.,Mariuzza, R.A. (deposition date: 2020-04-16, release date: 2021-04-21, Last modification date: 2023-10-18)

• Primary citation: Mishra, A.K.,Shahid, S.,Karade, S.S.,Agnihotri, P.,Kolesnikov, A.,Hasan, S.S.,Mariuzza, R.A.; CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.; Structure, 2023; PubMed: 37619561; DOI: 10.1016/j.str.2023.07.013

Experimental method

X-RAY DIFFRACTION (2.1 Å)