6WHC

CryoEM Structure of the glucagon receptor with a dual-agonist peptide

Summary for 6WHC

Entry DOI	10.2210/pdb6whc/pdb
EMDB information	21671
Descriptor	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywords	gpcr, receptor complex, membrane protein, agonist
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	163556.64
Authors	Belousoff, M.J.,Sexton, P.,Danev, R. (deposition date: 2020-04-07, release date: 2020-05-27, Last modification date: 2020-07-22)
Primary citation	Chang, R.,Zhang, X.,Qiao, A.,Dai, A.,Belousoff, M.J.,Tan, Q.,Shao, L.,Zhong, L.,Lin, G.,Liang, Y.L.,Ma, L.,Han, S.,Yang, D.,Danev, R.,Wang, M.W.,Wootten, D.,Wu, B.,Sexton, P.M. Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. J.Biol.Chem., 295:9313-9325, 2020 Cited by PubMed: 32371397 DOI: 10.1074/jbc.RA120.013793 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.4 Å)

Structure validation