6WGO

The interaction of dichlorido(3-(anthracen-9-ylmethyl)-1-methylimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL after 1 week

6WGO の概要

• エントリーDOI: 10.2210/pdb6wgo/pdb
• 分子名称: Lysozyme, SODIUM ION, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: metal-based, anticancer, ruthenium, nhc, carbene, hewl, hen egg white lysozyme, lysozyme, metallodrug, imidazole, dimethylimidazole, hydrolase
• 由来する生物種: Gallus gallus (Chicken)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14916.56

構造登録者

Sullivan, M.P.,Hartinger, C.G.,Goldstone, D.C. (登録日: 2020-04-06, 公開日: 2021-10-06, 最終更新日: 2023-10-18)

• 主引用文献: Lee, B.Y.T.,Sullivan, M.P.,Yano, E.,Tong, K.K.H.,Hanif, M.,Kawakubo-Yasukochi, T.,Jamieson, S.M.F.,Soehnel, T.,Goldstone, D.C.,Hartinger, C.G.; Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: In Vitro Anticancer Activity and Reactions with Biomolecules.; Inorg.Chem., 60:14636-14644, 2021; PubMed: 34528438; DOI: 10.1021/acs.inorgchem.1c01675

実験手法

X-RAY DIFFRACTION (1.3 Å)