6WEZ

Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H3 Hemagglutinin

Summary for 6WEZ

• Entry DOI: 10.2210/pdb6wez/pdb
• Descriptor: Hemagglutinin, heavy chain, light chain, ... (7 entities in total)
• Functional Keywords: antibody, influenza, hemagglutinin, stem epitope, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 4
• Total formula weight: 106182.25

Authors

Harshbarger, W.D.,Lockbaum, G.J.,Deming, D.T.,Attatippaholkun, N.,Schiffer, C.A.,Marasco, W.A. (deposition date: 2020-04-03, release date: 2020-11-25, Last modification date: 2024-04-03)

• Primary citation: Harshbarger, W.D.,Deming, D.,Lockbaum, G.J.,Attatippaholkun, N.,Kamkaew, M.,Hou, S.,Somasundaran, M.,Wang, J.P.,Finberg, R.W.,Zhu, Q.K.,Schiffer, C.A.,Marasco, W.A.; Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses.; Nat Commun, 12:559-559, 2021; PubMed: 33495478; DOI: 10.1038/s41467-020-20879-6

Experimental method

X-RAY DIFFRACTION (3.21 Å)