6WEX

Crystal Structure of Broadly Neutralizing Antibody 3I14-D93N Mutant Bound to the Influenza A H6 Hemagglutinin

Summary for 6WEX

Entry DOI	10.2210/pdb6wex/pdb
Descriptor	Hemagglutinin, Hemagglutinin HA2 chain, heavy chain, ... (5 entities in total)
Functional Keywords	antibody, influenza, hemagglutinin, stem epitope, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Influenza A virus More
Total number of polymer chains	4
Total formula weight	109265.24
Authors	Harshbarger, W.D.,Lockbaum, G.J.,Deming, D.T.,Attatippaholkun, N.,Schiffer, C.A.,Marasco, W.A. (deposition date: 2020-04-03, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Harshbarger, W.D.,Deming, D.,Lockbaum, G.J.,Attatippaholkun, N.,Kamkaew, M.,Hou, S.,Somasundaran, M.,Wang, J.P.,Finberg, R.W.,Zhu, Q.K.,Schiffer, C.A.,Marasco, W.A. Unique structural solution from a V H 3-30 antibody targeting the hemagglutinin stem of influenza A viruses. Nat Commun, 12:559-559, 2021 Cited by PubMed: 33495478 DOI: 10.1038/s41467-020-20879-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.49 Å)

Structure validation