6W92

Human UHRF1 TTD domain

Summary for 6W92

• Entry DOI: 10.2210/pdb6w92/pdb
• Descriptor: E3 ubiquitin-protein ligase UHRF1 (2 entities in total)
• Functional Keywords: ligase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 19212.29

Authors

Campbell, J.C.,Chang, L.,Sankaran, B.,Young, D.W. (deposition date: 2020-03-21, release date: 2021-02-24, Last modification date: 2023-10-18)

• Primary citation: Chang, L.,Campbell, J.,Raji, I.O.,Guduru, S.K.R.,Kandel, P.,Nguyen, M.,Liu, S.,Tran, K.,Venugopal, N.K.,Taylor, B.C.,Holt, M.V.,Young, N.L.,Samuel, E.L.G.,Jain, P.,Santini, C.,Sankaran, B.,MacKenzie, K.R.,Young, D.W.; Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery.; Sci Rep, 11:1121-1121, 2021; PubMed: 33441849; DOI: 10.1038/s41598-020-80588-4

Experimental method

X-RAY DIFFRACTION (1.3 Å)