6W92
Human UHRF1 TTD domain
Summary for 6W92
Entry DOI | 10.2210/pdb6w92/pdb |
Descriptor | E3 ubiquitin-protein ligase UHRF1 (2 entities in total) |
Functional Keywords | ligase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 19212.29 |
Authors | Campbell, J.C.,Chang, L.,Sankaran, B.,Young, D.W. (deposition date: 2020-03-21, release date: 2021-02-24, Last modification date: 2023-10-18) |
Primary citation | Chang, L.,Campbell, J.,Raji, I.O.,Guduru, S.K.R.,Kandel, P.,Nguyen, M.,Liu, S.,Tran, K.,Venugopal, N.K.,Taylor, B.C.,Holt, M.V.,Young, N.L.,Samuel, E.L.G.,Jain, P.,Santini, C.,Sankaran, B.,MacKenzie, K.R.,Young, D.W. Discovery of small molecules targeting the tandem tudor domain of the epigenetic factor UHRF1 using fragment-based ligand discovery. Sci Rep, 11:1121-1121, 2021 Cited by PubMed: 33441849DOI: 10.1038/s41598-020-80588-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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