6W1J

Cryo-EM structure of 5HT3A receptor in presence of Alosetron

6W1J の概要

• エントリーDOI: 10.2210/pdb6w1j/pdb
• EMDBエントリー: 21511 21512 21518
• 分子名称: 5-hydroxytryptamine receptor 3A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: transport protein
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 268894.53

構造登録者

Basak, S.,Chakrapani, S. (登録日: 2020-03-04, 公開日: 2021-01-13)

• 主引用文献: Basak, S.,Kumar, A.,Ramsey, S.,Gibbs, E.,Kapoor, A.,Filizola, M.,Chakrapani, S.; High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.; Elife, 9:-, 2020; PubMed: 33063666; DOI: 10.7554/eLife.57870

実験手法

ELECTRON MICROSCOPY (2.92 Å)