6W03
Crystal Structure of HIV-1 BG505 DS-SOSIP.3mut Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.3 Angstrom
6W03 の概要
エントリーDOI | 10.2210/pdb6w03/pdb |
分子名称 | Envelope glycoprotein gp41, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
機能のキーワード | hiv-1 envelope prefusion trimer, viral protein, viral protein-immune system complex, viral protein/immune system |
由来する生物種 | Human immunodeficiency virus 1 詳細 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 156590.45 |
構造登録者 | |
主引用文献 | Chuang, G.Y.,Lai, Y.T.,Boyington, J.C.,Cheng, C.,Geng, H.,Narpala, S.,Rawi, R.,Schmidt, S.D.,Tsybovsky, Y.,Verardi, R.,Xu, K.,Yang, Y.,Zhang, B.,Chambers, M.,Changela, A.,Corrigan, A.R.,Kong, R.,Olia, A.S.,Ou, L.,Sarfo, E.K.,Wang, S.,Wu, W.,Doria-Rose, N.A.,McDermott, A.B.,Mascola, J.R.,Kwong, P.D. Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses. J.Virol., 94:-, 2020 Cited by PubMed: 32295908DOI: 10.1128/JVI.00074-20 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
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