6VZB
Crystal structure of cytochrome P450 NasF5053 S284A-V288A mutant variant from Streptomyces sp. NRRL F-5053 in the cyclo-L-Trp-L-Pro-bound state
Summary for 6VZB
Entry DOI | 10.2210/pdb6vzb/pdb |
Descriptor | cytochrome P450 NasF5053, (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, SODIUM ION, ... (5 entities in total) |
Functional Keywords | biosynthetic protein, cytochrome p450, cyclodipeptide, regio-selecitivty, stereo-selectivity, pyrroloindoline alkaloids, radical mediated reaction, f5053, streptomyces, oxidoreductase |
Biological source | Streptomyces sp. NRRL F-5053 |
Total number of polymer chains | 1 |
Total formula weight | 44621.15 |
Authors | |
Primary citation | Sun, C.,Luo, Z.,Zhang, W.,Tian, W.,Peng, H.,Lin, Z.,Deng, Z.,Kobe, B.,Jia, X.,Qu, X. Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines. Nat Commun, 11:6251-6251, 2020 Cited by PubMed: 33288748DOI: 10.1038/s41467-020-20022-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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